A UNIQUE RHINOLOGIC MANIFESTATION OF MULTIPLE MYELOMA

A unique rhinologic manifestation of multiple myeloma

Objectives: To describe unusual vascular lesions in the nasal mucosa of a patient with multiple myeloma (MM), presenting with recurrent epistaxis.Materials and Methods: An extensive literature review was done looking for previous reports describing epistaxis secondary to nasal mucosa abnormalities in patients with MM.Medical Skirts records of a pat

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Factor XIII deficiency in a mother-baby dyad

Background: Factor XIII deficiency is a rare autosomal recessive coagulation disorder with varied presentations including prolonged bleeding from the umbilical cord stump, defective wound healing, recurrent miscarriages, or life-threatening intracranial hemorrhage.Clinical Description: A male Skirts baby was born at term gestation to a fourth gravi

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Long-term airborne measurements of pollutants over the United Kingdom to support air quality model development and evaluation

The ability of regional air quality models to skilfully represent pollutant distributions throughout the atmospheric column is important to enabling their skilful prediction at the surface.This provides a requirement for model evaluation at elevated altitudes, though observation datasets available for this purpose are limited.This is particularly t

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Association of immune response with efficacy and safety outcomes in adults with phenylketonuria administered pegvaliase in phase 3 clinical trialsResearch in context

Background: This study assessed the immunogenicity of pegvaliase (recombinant Anabaena variabilis phenylalanine [Phe] ammonia lyase [PAL] conjugated with polyethylene Wine / Sake Cups glycol [PEG]) treatment in adults with phenylketonuria (PKU) and its impact on safety and efficacy.Methods: Immunogenicity was assessed during induction, upward titra

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